Senior Scientist, Translational Medicine

Horizon Therapeutics Washington, Washington DC
senior translational medicine horizon data collaborate team translational medicine cross functional analysis collaboration disease phd immunology
October 11, 2022
Horizon Therapeutics
Washington, Washington DC
FULL_TIME
Working at Horizon is more than a job - it's personal. For us, success is measured by the numbers that matter most - the number of lives we touch, the number we change and those we work tirelessly to help save. We're a team of agile, out-of-the-box thinkers who are inspired to do more because we know we're a part of something bigger. We strive to build meaningful careers at a company whose values we share because when we live up to our potential, we help others live up to theirs.

Position Summary:

Responsibilities:
  • Develop and execute translational strategies to achieve project-specific goals and objectives for investigational therapeutics in clinical development.
  • Represent the Translational Medicine function in cross-functional drug development teams.
  • Work within a matrixed, cross functional team to provide end to end oversight of biomarker sample collection, testing and analysis.
  • Initiate and oversee contracting and sample analysis with CROs to execute biomarker testing plans.
  • Track budgets and deliverables.
  • Establish fit for purpose biomarker assays internally or with third party vendors.
  • Guide data analyses in collaboration with Horizon Biometrics and Quantitative Biology colleagues to deliver informative analyses to support internal decision making, regulatory interactions and publications/abstracts.
  • Collaborate with Horizon Research and Commercial to provide scientific input into new disease indications under consideration
  • Collaborate with academics to initiate and carry out Ph0 studies to generate disease relevant biomarker data and insights into biomarker defined patient subgroups and endotypes.
  • Collaborate with Horizon Translational Medicine and Translational Science colleagues to ensure aligned strategy for each clinical asset.

Qualifications and Skills Required:
  • PhD in Immunology or relevant scientific discipline; minimum PhD +4-6 year (or BS + 13-15 year, MS +10-13 year)
  • A calling to develop new therapies for patients with immune diseases.
  • A broad understanding of cellular and molecular pharmacology concepts within the autoimmunity and/or immunology field is essential.
  • Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity.
  • Prior experience with clinical trials is preferred but not essential
  • Prior experience in biopharma is an advantage
  • Hands on experience with assay development and optimization
  • Familiarity with a variety of assay platforms
  • Willingness to perform lab work when necessary
  • Prior experience analyzing big data sets
  • Detailed orientated approach
  • Proven planning, organization, and project management skills
  • Proficient in Microsoft Office.
  • Professional, proactive demeanor.
  • Strong interpersonal skills.
  • Excellent written and verbal communication skills.

Horizon Core Values & Competencies:

Growth
  • Manages Ambiguity
  • Strategic Mindset
  • Demonstrates Self-awareness
  • Cultivates Innovation
  • Develops Talent

Accountability
  • Drives Results
  • Ensures Accountability
  • Decision Quality

Transparency
  • Courage
  • Collaboration
  • Instills Trust

Horizon requires all U.S. employees to be fully vaccinated, as a condition of employment, with either Pfizer (fully approved by the U.S. Food and Drug Administration), Moderna or Johnson & Johnson (currently granted emergency-use authorization by the FDA). "Fully vaccinated" is defined as two weeks after your final dose of the Pfizer, Moderna, or Johnson & Johnson vaccine. Horizon will provide medical and religious accommodations as required by law.

Horizon Therapeutics plc does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, age, disability, veteran status, or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. Any individual, who, because of a disability, needs accommodation or assistance in completing this application or at any time during the application process, should contact the Human Resources Department.

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