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Sr Scientist, Lab Automation

Takeda Pharmaceutical Weymouth, Massachusetts
scientist automation automation data chemistry engineers chemical design platforms robotics optimization technical science
November 21, 2022
Takeda Pharmaceutical
Weymouth, Massachusetts
FULL_TIME

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Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Sr Scientist, Lab Automation where you will manage the development of sustainable and cost-effective processes for the manufacture of new synthetic molecule pharmaceuticals, along with methods for achieving and controlling high standards of purity and quality. You will also design and apply automation tools (high and medium throughput experimentation, data rich experimentation and robotics) across all phases of the process development lifecycle to accelerate route selection, process design/optimization and characterization, that will be deployable across the global organization. As part of the Process Chemistry, you will report to Director, Process Chemistry & Development.

How you will contribute:
  • Partner with Data Scientists, Process Modeling SMEs and Automation Engineers to develop practices for the capture, organization, contextualization, visualization and storage of the generated data, to enhance process understanding and promote data-driven decision-making.

  • Contribute to the development of the department's automation strategy and guide the development of new automation approaches.

  • Be the project and technical lead for interdisciplinary departmental and cross-functional workstreams.

  • Stay current on new trends, new technologies, and external communities and consortia related to, eg, Synthetic Innovation, Digital Lab, Advanced Automation, Robotics and Cobotics.

  • Develop wet- and dry-lab solutions in the context of Advanced & High-Throughput Automation, Robotics and Cobotics.

  • Work on automation technology projects end to end, from project planning to implementation.

  • Identify opportunities to accelerate process development activities and implement them by using automation techniques.

  • Partner with Process Engineers & PAT experts to develop automated and autonomous chemical reaction optimization platforms.

  • Work in collaboration with internal and external partners to develop next-generation automation solutions.

  • Partner with Control Engineers to integrate different equipment, sensors, controllers and industrial systems of varying communication protocols.

  • Independently design and execute experiments.

  • Help develop the department's automation strategy and communicates complex data/decisions within department and cross functionally.

  • Define capital, IT, and facilities requirements for automation efforts, and deliver solutions with business partners.

  • Organize, evaluates and presents data.

  • Learn and utilize data science tools and apply these methods to automation.

  • Develop and share best practices across PCD global sites.

  • Grow and develop an entrepreneurial network to further enhance the impact that automation can have on the broader PCD and PharmSci function.

  • Analyze technical issues and coordinates potential resolution with team members.

  • Build and maintain relationships with key vendors and assists with technical aspects of vendor negotiations.

  • Author relevant sections of regulatory documents, reports and pier reviewed manuscripts.

  • Represent Takeda and be an active member on pre-competitive collaborations with academic and industrial partners.

Minimum Requirements/Qualifications:
  • Bachelors degree in Chemistry of Chemical engineering and 11+ years relevant industry experience

  • Masters degree in Chemistry, Chemical engineering or related pharmaceutical science 9+ years relevant industry experience

  • PhD in Chemistry, Chemical engineering or related pharmaceutical science and 3+ years relevant industry experience

  • Demonstrated experience in the successful design and implementation of automated systems.

  • Experience in parallel optimization of reaction conditions.

  • Previous work with automated platforms such as Unchained Labs, Chemspeed technologies, Amigochem and the Mettler Toledo suite of reactors.

  • Familiarity with both wet and solid-state analytical techniques (eg UPLC, GC, XRPD, Raman).

  • The ability to collaborate within an interdisciplinary scientific team comprised of organic and analytical chemists, chemical engineers, data scientists and control engineers

  • Experience translating scientific processes to automation platforms and to identify new application areas.

  • Experience troubleshooting and diagnosing problems in analytical and automated platforms

  • Experience in data analytics and programming (R, Python, Tableau, SQL, JMP, etc.) is preferred. An interest to develop data analytics and programming skills.

  • Subject matter expert with knowledge of applicable lab equipment and operations.

  • May require approximately 5-10% travel.

What Takeda can offer you:
  • Comprehensive Healthcare: Medical, Dental, and Vision

  • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs and company match of charitable contributions

  • Family Planning Support

  • Flexible Work Paths

  • Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time

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